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Nestabilna angina dostikrat pomeni poslabšanje oziroma napredovanje koronarne bolezni in je zelo nevarna. Del obloge na žili se lahko odlušči in s tem žilo dodatno zamaši, se pravi, da v srce pride še manj krvi. Ludwig's angina is a type of severe cellulitis involving the floor of the mouth. Early on the floor of the mouth is raised and there is difficulty swallowing saliva, which may run from the person's mouth. As the condition worsens, the airway may be compromised with hardening of.
Ludwig's angina Synonyms Angina Ludovici Swelling in the area in a person with Ludwig's angina., Symptoms Fever, pain, a raised tongue, trouble swallowing, neck swelling Airway compromise Usual onset Rapid Based on symptoms and examination, Treatment, Ludwig's angina is a type of severe involving the floor of the mouth. Early on the floor of the mouth is raised and there is difficulty swallowing saliva, which may run from the person's mouth.
As the condition worsens, the airway may be compromised with hardening of the spaces on both sides of the tongue. This condition has a rapid onset over hours.
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The majority of cases follow a. Other causes include a, cut or piercing inside the mouth,. It is a spreading infection of connective tissue through tissue spaces, normally with virulent and invasive organisms. It specifically involves the,. Prevention is by appropriate dental care including management of dental infections. Initial treatment is generally with. In more advanced cases or may be required.
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With the advent of antibiotics in 1940s, improved oral and dental hygiene, and more aggressive surgical approach, the rates and risk of death among those infected has significantly reduced. It is named after a German physician, who first described this condition in 1836. Contents. Signs and symptoms Ludwig's angina is a form of severe diffuse with bilateral involvement, primarily of the submandibular space with the sublingual and submental spaces also being involved. It presents with an acute onset and spreads very rapidly meaning early diagnosis and immediate treatment planning is key to saving lives. The external signs may include bilateral lower facial around the mandible and upper neck.
Signs inside the mouth may include elevation of the floor of mouth due to sublingual space involvement and posterior displacement of the tongue, creating the potential for a compromised airway. Additional symptoms may include painful neck swelling, tooth pain, shortness of breath, fever, and general malaise. Stridor, and may also be seen when an impending airway crisis is nearing. Cause The most prevalent cause of Ludwig's angina is odontogenic, accounting for approximately 75% to 90% of cases.
Infections of the lower second and third molars are usually implicated due to their roots extending inferiorly below the mylohyoid muscle. Periapical abscesses of these teeth also result in lingual cortical penetration, leading to submandibular infection. However, oral ulcerations, infections of oral malignancy, mandible fracture, bilateral sialolithiasis-related submandibular gland infection, and penetrating injuries of the mouth floor have also been reported as potential causes of Ludwig's angina. In fact, the same microorganisms responsible for less morbid head and neck infections are found in causing extensive infection throughout the floor of mouth and neck when Ludwig's angina is critically reviewed. Patient with systemic illness, such as diabetes mellitus, malnutrition, compromised immune system, and organ transplantation are also commonly predisposed to Ludwig's angina. It is found that one third of the cases of Ludwig's angina are associated with systemic illness. A review reporting the incidence of illnesses associated with Ludwig angina found that 18% of cases involved diabetes mellitus, 9% involved acquired immune deficiency syndrome, and another 5% were human immunodeficiency virus (HIV) positive.
Diagnosis Infections originating in the roots of teeth can be identified with a. A CT scan of the neck with contrast material is used to identify deep neck space infections. If there is suspicion of the, a is sometimes done. Angioneurotic oedema, and formation following anticoagulation should be ruled out as possible diagnoses.
Microbiology There are a few methods that can be used for determining the microbiology of Ludwig's angina. One of the traditionally used methods is taking although it has some limitations. By taking pus samples from a patient with Ludwig's angina, the microbiology were found to be commonly polymicrobial. Some of the commonly found microbes are,. Treatment For each patient, the treatment plan should be done with consideration of each of the individual patient's differing factors. They are namely the stage of the disease and co-morbid conditions at the time of presentation, physician experience, available resources, and personnel are critical factors in formulation of a treatment plan. There are four principles that guide the treatment of Ludwig's Angina: Sufficient airway management, early and aggressive antibiotic therapy, incision and drainage for any who fail medical management or form localized abscesses, and adequate nutrition and hydration support.
Each will be explained in detail below. Airway management. Placement of an endotracheal tube to aid breathing. Airway management has been found to be the most important factor in treating patients with Ludwig's Angina, i.e. It is the “primary therapeutic concern”.
Airway compromise is known to be the leading cause of death from Ludwig's Angina. The basic method to achieve this is to allow the patient to sit in an upright position, with supplemental oxygen provided by masks or nasal prongs. Patients should never be left unattended, particularly if there is an absence of intubation or a surgical airway in place. Methods of airway management range from conservative airway management – consisting of close observation and intravenous, to airway intervention with intubation. If the oxygen saturation levels are adequate and have been given, simple airway observation can be done. This is a suitable method to adopt in the management of children, as a retrospective study described that only 10% of children required airway control. However, a tracheostomy was performed on 52% of those affected with Ludwig's Angina over 15 years old.
Airway control is compulsory if a surgical procedure is required. Flexible nasotracheal intubation require skills and experience. If nasotracheal intubation is not possible, and under local anaesthetic can be done. This procedure is carried out on patients with advanced stage of Ludwig's Angina.
Endotracheal intubation has been found to be in association with high failure rate with acute deterioration in respiratory status. Elective is described as a safer and more logical method of airway management in patients with fully developed Ludwig's Angina. Fibre-optic nasoendoscopy can also be used, especially for patients with swellings.
It is important that incision and drainage are preceded by consulting the about possible airway problems at intubation. A tracheostomy set should always be present in the operating room in case there is requirement for local tracheostomy or an emergency. Antibiotics. Antibiotic therapy is, it is given until results are obtained. The empirical therapy should be effective against both and species commonly involved in Ludwig's Angina. Only when culture and sensitivity results return should therapy be tailored to the specific requirements of the patient.
Empirical coverage should consist of either a with a such as / with or a resistant antibiotic such as, imipenem. This should be given in combination with a drug effective against anaerobes such as.
Parenteral antibiotics are suggested until the patient is no longer for at least 48 hours. Oral therapy can then commence to last for 2 weeks, with with,. Incision and drainage. Surgical are the main methods in managing severe and complicated deep neck infections that fail to respond to medical management within 48 hours.
It is indicated in cases of:. Airway compromise.
Deteriorating condition. Descending infection. Palpable or radiographic evidence of formation. Bilateral incisions should be carried out in addition to a midline incision. Access to the supramylohyoid spaces can be gained by through the muscle from below. are recommended in both supramylohyoid and inframylohyoid spaces bilaterally. In addition, through and through drains from the space to the space on both sides should be placed as well.
The process is completed with the of and thorough irrigation. It is necessary to mark drains in order to identify their location. They should be with loops as well so it will be possible to advance them without re-anaesthetizing the patient while drains are re-sutured to the skin. An absorbent is then applied. A bandnet dressing retainer can be constructed so as to prevent the use of tape.
Nutritional support Adequate nutrition and hydration support is essential in deciding the outcomes in any patient following surgery, particularly young children. In this case, pain and swelling in the neck region would usually cause difficulties in eating or swallowing, hence reducing patient's food and fluid intake. As a result, patients suffer from weight loss due to loss of fat, muscle and skin initially, followed by bone and internal organs in the late phase. Meanwhile, at the cellular level, the cells would be less able to maintain homeostasis in the presence of stressors such as infection and surgery. Patients must therefore be well-nourished and hydrated to promote wound healing and to fight off infection. Post-operative care , which is the removal of endotracheal tube to liberate the patient from mechanical ventilation, should only be done when the patient's airway is proved to be patent, allowing adequate breathing.
This is indicated by a decrease in swelling and patient's capability of breathing adequately around an uncuffed with the lumen blocked. During the hospital stay, patient's condition will be closely monitored by:. carrying out cultures and sensitivity tests to decide if any changes need to be made to patient's antibiotic course.
observing patient's body temperature - a rise implies further infection. monitoring patient's count - a decrease implies effective and sufficient drainage. repeating to prove patient's restored health status or if infection extends, the anatomical areas that are affected. Moreover, it is advised to never leave young children with significant neck swelling unattended and they should always be seated to prevent suffocation. Etymology The term “angina”, is derived from the Latin word “ angere”, which means “choke”; and the Greek word “ ankhone”, which means “strangle”. Placing it into context, Ludwig's angina refers to the feeling of strangling and choking, secondary to obstruction of the airway, which is the most serious potential complication of this condition.
See also. References.